منابع مشابه
Biosynthetic origin of hygromycin A.
Hygromycin A, an antibiotic produced by Streptomyces hygroscopicus, is an inhibitor of bacterial ribosomal peptidyl transferase. The antibiotic binds to the ribosome in a distinct but overlapping manner with other antibiotics and offers a different template for generation of new agents effective against multidrug-resistant pathogens. Reported herein are the results from a series of stable-isoto...
متن کاملBiosynthetic Origin of Serum Cholesterol
INTRODUCTION Although cholesterol is synthesized in the adult by virtually all tissues with the exception of the cenThe results of this paper have been presented at the 1966 meetings of the Southern Society for Clinical Investigation and the American Society for Clinical Investigation and have been published in abstract form (1, 2). Dr. Wilson is a recipient of a career development award from t...
متن کاملOrigin of Saxitoxin Biosynthetic Genes in Cyanobacteria
BACKGROUND Paralytic shellfish poisoning (PSP) is a potentially fatal syndrome associated with the consumption of shellfish that have accumulated saxitoxin (STX). STX is produced by microscopic marine dinoflagellate algae. Little is known about the origin and spread of saxitoxin genes in these under-studied eukaryotes. Fortuitously, some freshwater cyanobacteria also produce STX, providing an i...
متن کاملEvidence for a gibberellin biosynthetic origin of ceratopteris antheridiogen.
The species-specific chemical messenger, antheridiogen A(Ce), mediates the differentiation of male gametophytes in the fern Ceratopteris. In order to investigate the biochemical origin of antheridiogen, the effect of the inhibitors, 2'-isopropyl-4'-(trimethylammoniumchloride)-5' -methylphenylpiperidine-1-carboxylate (AMO-1618), 2-chloroethyl trimethylammonium chloride (CCC), and alpha-cycloprop...
متن کاملBiosynthetic origin and functional significance of murine platelet factor V.
Factor V (FV), a central regulatory protein in hemostasis, is distributed into distinct plasma and platelet compartments. Although platelet FV is highly concentrated within the platelet alpha-granule, previous analysis of human bone marrow and liver transplant recipients has demonstrated that platelet FV in these individuals originates entirely from the uptake of plasma FV. In order to examine ...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2003
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.47.7.2065-2071.2003